Table 2.6. Number and rates* of newly reported cases of chronic hepatitis B virus infection, by demographic characteristics — United States, 2019

Table 2.6. Number and rates* of newly reported cases† of chronic hepatitis B virus infection, by demographic characteristics — United States, 2019
Table 2.2.
Characteristics No. Rate*
Total § 13,859 5.9
Age group (years)
0-19 265 0.5
20-29 1,703 5.4
30-39 3,490 11.3
40-49 3,020 10.7
50-59 2,562 8.4
≥60 2,809 5.1
Sex
Male 7,985 7.0
Female 5,853 4.9
Race/ethnicity
American Indian/Alaska Native 24 1.0
Asian/Pacific Islander 2,119 18.9
Black, non-Hispanic 2,198 6.7
White, non-Hispanic 2,807 1.8
Hispanic 444 1.4
Urbanicity ¶
Urban 12,372 6.3
Rural 1,249 3.5
HHS Region: Regional Office #
Region 1: Boston 322 3.6
Region 2: New York 1,687 6.0
Region 3: Philadelphia 2,392 7.9
Region 4: Atlanta 4,984 9.1
Region 5: Chicago 2,203 4.2
Region 6: Dallas 527 4.9
Region 7: Kansas City 604 4.3
Region 8: Denver 385 3.1
Region 9: San Francisco 98 1.3
Region 10: Seattle 657 4.6
Source: CDC, National Notifiable Diseases Surveillance System.
* Rates per 100,000 population.
† Reported cases that met the classification criteria for a confirmed case. For the case definition, see https://ndc.services.cdc.gov/conditions/hepatitis-b-chronic/.
§ Numbers reported in each category might not add up to the total number of reported cases in a year because of cases with missing data or, in the case of race/ethnicity, cases categorized as “Other.”
¶ Urban-rural region was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities (https://www.cdc.gov/nchs/data_access/urban_rural.htm). Large central metropolitan, large fringe metropolitan, medium metropolitan, and small metropolitan counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.
# US Department of Health and Human Services Regions (HHS) were categorized according to the grouping of states and US territories assigned under each of the 10 HHS regional offices (https://www.hhs.gov/about/agencies/iea/regional-offices/index.html). For the purposes of this report, regions with US territories (Regions 2 and 9) contain data from states only.

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During 2019, the rate of newly reported chronic hepatitis B was highest among persons aged 30–49 years and accounted for 47% of all chronic hepatitis B cases reported during 2019. Approximately 89% of all newly reported chronic hepatitis B cases occurred in urban areas, as defined by the National Center for Health Statistics, and approximately one-third were reported from US Department of Health and Humans Services Region 4 (Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee).

Although the rate of reported acute hepatitis B among Asian/Pacific Islander persons (Figure 2.6) was the lowest among all racial/ethnicity groups, the rate of newly reported chronic hepatitis B was highest among Asian/Pacific Islander persons (18.9 reported cases per 100,000 population) >10 times the rate among non-Hispanic White persons. Because the majority of prevalent chronic hepatitis B virus infections in the United States are among persons who are non–US-born, differences in the rates of newly reported chronic hepatitis B by race/ethnicity are likely influenced by country of birth. However, country of birth is not routinely collected in National Notifiable Diseases Surveillance System.

Source: Patel EU, Thio CL, Boon D, et al. Prevalence of hepatitis B and hepatitis D virus infections in the United States, 2011–2016. Clin Infect Dis 2019;69:709–12. doi: https://doi.org/10.1093/cid/ciz001
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