Volume 11, Number 8, August 2005

Virology, Pathology, and Clinical Manifestations of West Nile Virus Disease

Edward B. Hayes,* James J. Sejvar,† Sherif R. Zaki,† Robert S. Lanciotti,* Amy V. Bode,* and Grant L. Campbell*
*Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; and †Centers for Disease Control and Prevention, Atlanta Georgia, USA

Figure. Histopathologic features of West Nile virus (WNV) in human tissues. Panels A and B show inflammation, microglial nodules, and variable necrosis that occur during WNV encephalitis; panel C shows WNV antigen (red) in neurons and neuronal processes using an immunohistochemical stain; panel D is an electron micrograph of WNV in the endoplasmic reticulum of a nerve cell (arrow). Bar = 100 nm.

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This page last reviewed July 18, 2005

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention